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MOUTHRİNSES AND PALATAL DONOR SİTE HEALİNG AFTER FREE GİNGİVAL GRAFT
Sponsor: Yuzuncu Yil University
Summary
This single-blind randomized controlled clinical trial aimed to compare the effects of hypochlorous acid, hyaluronic acid, and chlorhexidine mouthrinses on palatal donor site healing following free gingival graft surgery. Fifty-four patients requiring free gingival graft surgery were randomly assigned to one of three mouthrinse groups. Clinical wound healing, wound dimensions, epithelialization, tissue consistency, bleeding control, and postoperative pain were evaluated during a 28-day follow-up period. The findings of this study may contribute to the identification of an effective postoperative mouthrinse for improving palatal donor site healing and patient comfort.
Official title: COMPARİSON OF HYPOCHLOROUS ACİD, HYALURONİC ACİD, AND CHLORHEXİDİNE MOUTHRİNSES ON PALATAL DONOR SİTE HEALİNG FOLLOWİNG FREE GİNGİVAL GRAFT SURGERY: A SİNGLE-BLİND CONTROLLED CLİNİCAL TRİAL
Key Details
Gender
All
Age Range
18 Years - 55 Years
Study Type
INTERVENTIONAL
Enrollment
54
Start Date
2020-06-20
Completion Date
2021-07-07
Last Updated
2026-07-08
Healthy Volunteers
No
Interventions
Hypochlorous Acid
Commercially available hypochlorous acid mouthrinse (Crystalin®, NHP İlaç San. ve Tic. A.Ş., Ankara, Türkiye). Participants rinsed with 15 mL for 60 seconds three times daily for 14 days beginning 24 hours after free gingival graft surgery.
Hyaluronic Acid (HA)
Commercially available hyaluronic acid mouthrinse (Gengigel®, Ricerfarma, Milan, Italy). Participants rinsed with 15 mL for 60 seconds three times daily for 14 days beginning 24 hours after free gingival graft surgery.
Chlorhexidine gluconate 0.2%
Commercially available 0.2% chlorhexidine gluconate mouthrinse (Kloroben®, Drogsan, Ankara, Türkiye). Participants rinsed with 15 mL for 60 seconds three times daily for 14 days beginning 24 hours after free gingival graft surgery.
Locations (1)
Van Yuzuncu Yil University Faculty of Dentistry
Van, Tuşba, Turkey (Türkiye)