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NOT YET RECRUITING
NCT07690384
NA

Effects of Functional Oils on Obesity With Mild Cognitive Impairment

Sponsor: Capital Medical University

View on ClinicalTrials.gov

Summary

The purpose of this study is to investigate the effects of diacylglycerol (DAG) oil on obesity accompanied by mild cognitive impairment (MCI). Participants aged 45 to 75 years with obesity and MCI will be randomly assigned to two groups: a control group receiving regular rapeseed oil (RSO) and an experimental group receiving rapeseed-based DAG oil. The dietary intervention will last for 6 months. The main goal is to observe whether this functional oil intervention can improve cognitive function and regulate white adipose tissue browning.

Official title: Interventional Study of Functional Oils Improving Obesity With Mild Cognitive Impairment Via Regulating White Adipose Tissue Browning

Key Details

Gender

All

Age Range

45 Years - 75 Years

Study Type

INTERVENTIONAL

Enrollment

100

Start Date

2026-07

Completion Date

2027-03

Last Updated

2026-07-08

Healthy Volunteers

No

Interventions

DIETARY_SUPPLEMENT

Rapeseed Oil (RSO)

A commercially available conventional rapeseed oil for daily household cooking use, containing diacylglycerol (DAG) only at the trace level naturally occurring in regular vegetable oil.

DIETARY_SUPPLEMENT

Diacylglycerol Oil (DAG Oil)

A rapeseed oil-based functional oil produced via lipase-catalyzed enzymatic conversion, with a diacylglycerol content ≥40% (national standard requirement), for daily household cooking use in place of conventional cooking oil.

Locations (1)

Capital Medical University

Beijing, Beijing Municipality, China