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NCT07691216

Retrospective Observational Multicenter Study on the Burden of Hospitalized Patients With Respiratory Tract Infection

Sponsor: LOGEX

View on ClinicalTrials.gov

Summary

This multicenter retrospective real-world data study will evaluate the burden of respiratory tract infection (RTI)-related hospitalizations in up to 10 Dutch hospitals between 2018 and 2026. The study aims to quantify: * Hospitalization rates * Healthcare resource utilization (LOS, ICU admissions, readmissions) * Clinical outcomes (including mortality) * Direct healthcare costs * Pathogen-specific burden (e.g., RSV, influenza, SARS-CoV-2) Using linked hospital, laboratory, and administrative data, outcomes will be analyzed by age group, comorbidities, pathogen, and respiratory season. The expected cohort size is approximately 60,000-70,000 patients. The results will provide evidence to support Dutch public health policy, including RSV immunization strategies, healthcare capacity planning, and antimicrobial stewardship.

Official title: Retrospective Observational Multicenter Study on the Burden, Resource Utilization, and Outcomes of Hospitalized Patients With Respiratory Tract Infections in Dutch Hospitals.

Key Details

Gender

All

Age Range

Any - Any

Study Type

OBSERVATIONAL

Enrollment

70000

Start Date

2026-08-01

Completion Date

2027-06-30

Last Updated

2026-07-08

Healthy Volunteers

No

Interventions

OTHER

Respiratory tract infection hospitalisation

Hospitalisation with a primary or secondary ICD-10 diagnosis of respiratory tract infection (RTI), including infections caused by RSV, influenza, SARS-CoV-2, and other viral or bacterial pathogens, identified through routine administrative and laboratory data.