Clinical Research Directory

Inclusion Criteria: 1. Male and female participants aged 18-70 (including those who are 18 and 70 years old)； 2. Pathologically or cytologically confirmed ductal adenocarcinoma of the pancreas; and subjects must have at least one measurable lesion as defined by Response Evaluation Criteria in Solid Tumors (RECIST, version 1.1); 3. Life expectancy ≥ 12 weeks; 4. Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 or 1; 5. Adequate marrow and organ function; Exclusion Criteria: 1. Prior receipt of any anti-tumor therapy, including but not limited to systemic chemotherapy, radiotherapy, interventional therapy, immunotherapy, targeted therapy, and anti-tumor traditional Chinese medicine therapy; 2. Presence of distant metastatic lesions confirmed by imaging; 3. Known hypersensitivity to the investigational drug or any of its excipients; 4. Presence of any serious or uncontrolled systemic disease; 5. History of allogeneic hematopoietic stem cell transplantation or solid organ transplantation; 6. Clinically significant acute or chronic pancreatitis; 7. Participation in any interventional clinical trial involving drugs or medical devices within 4 weeks prior to the first administration of study treatment; 8. Vaccination with live or live-attenuated vaccines within 4 weeks prior to the first dose of the investigational drug; 9. Any other condition that, in the judgment of the investigator, makes the subject unsuitable for enrollment.