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NOT YET RECRUITING

NCT07693153

PHASE1

The Effects of Psilocybin on Social Connectedness

Sponsor: Yale University

View on ClinicalTrials.gov

Summary

The study is a randomized, double-blind, placebo-controlled, expectancy-controlled, mechanistic trial. This study looks to explore whether a single dose of psilocybin (25mg) reduces amygdala reactivity to negative socioemotional stimuli during the Facial Emotion Recognition Task (FERT) compared to a placebo in adults who feel lonely or those with unresolved grief symptoms.

Key Details

Gender

All

Age Range

21 Years - 65 Years

Study Type

INTERVENTIONAL

Enrollment

Start Date

2026-08-31

Completion Date

2031-12-15

Last Updated

2026-07-09

Healthy Volunteers

Yes

Conditions

Loneliness Grief

Interventions

DRUG

Psilocybin

25 mg

DRUG

Placebo

Placebo capsule

Locations (1)

Connecticut Mental Health Center

New Haven, Connecticut, United States