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Innovative Ovarian Cancer Biomarker Assays
Sponsor: National and Kapodistrian University of Athens
Summary
Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes. Recent research has focused on the development of blood-based tests, sometimes referred to as liquid biopsy tests, which aim to look for changes in the blood that could be linked to cancer. These tests are still under investigation and are not part of routine clinical care. The purpose of this study is to evaluate several blood-based ovarian cancer tests. This will be done by comparing test results from people who have ovarian cancer with results from people who do not have cancer. The study will also collect information from standard blood tests and genetic analyses to better understand how these results relate to ovarian cancer. This study is for research purposes only. The blood-based tests being evaluated are investigational and are not used to make medical decisions or diagnoses for women taking part in the study.
Official title: Multi-site, Multi-country Evaluation of Innovative Ovarian Cancer Biomarker Assays. (DISARM Clinical Study B-CSB)
Key Details
Gender
FEMALE
Age Range
35 Years - Any
Study Type
OBSERVATIONAL
Enrollment
2080
Start Date
2026-08-03
Completion Date
2028-12
Last Updated
2026-10-01
Healthy Volunteers
Yes
Conditions
Interventions
Investigational ovarian cancer biomarker assays
Collection of blood samples for investigational ovarian cancer biomarker analyses (OVA-GLY, OVA-VOC and OVA-miRNA).
Locations (7)
Vseobecna Fakultni Nemocnice V Praze
Prague, Czechia
Fakultni Nemocnice Bulovka
Prague, Czechia
National Centre for Scientific Research Demokritos
Athens, Attica, Greece
Dept of Clinical Therapeutics, Alexandra Hospital
Athens, Greece
Lithuanian University of Health Sciences
Kaunas, Lithuania
Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.
Lisbon, Portugal
Imperial College Healthcare NHS Trust Hammersmith Hospital
London, United Kingdom