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RECRUITING
NCT07693894

Innovative Ovarian Cancer Biomarker Assays

Sponsor: National and Kapodistrian University of Athens

View on ClinicalTrials.gov

Summary

Ovarian cancer is often diagnosed at a later stage because early symptoms can be mild or non-specific. Earlier detection of ovarian cancer could improve treatment options and outcomes. Recent research has focused on the development of blood-based tests, sometimes referred to as liquid biopsy tests, which aim to look for changes in the blood that could be linked to cancer. These tests are still under investigation and are not part of routine clinical care. The purpose of this study is to evaluate several blood-based ovarian cancer tests. This will be done by comparing test results from people who have ovarian cancer with results from people who do not have cancer. The study will also collect information from standard blood tests and genetic analyses to better understand how these results relate to ovarian cancer. This study is for research purposes only. The blood-based tests being evaluated are investigational and are not used to make medical decisions or diagnoses for women taking part in the study.

Official title: Multi-site, Multi-country Evaluation of Innovative Ovarian Cancer Biomarker Assays. (DISARM Clinical Study B-CSB)

Key Details

Gender

FEMALE

Age Range

35 Years - Any

Study Type

OBSERVATIONAL

Enrollment

2080

Start Date

2026-08-03

Completion Date

2028-12

Last Updated

2026-10-01

Healthy Volunteers

Yes

Conditions

Interventions

DIAGNOSTIC_TEST

Investigational ovarian cancer biomarker assays

Collection of blood samples for investigational ovarian cancer biomarker analyses (OVA-GLY, OVA-VOC and OVA-miRNA).

Locations (7)

Vseobecna Fakultni Nemocnice V Praze

Prague, Czechia

Fakultni Nemocnice Bulovka

Prague, Czechia

National Centre for Scientific Research Demokritos

Athens, Attica, Greece

Dept of Clinical Therapeutics, Alexandra Hospital

Athens, Greece

Lithuanian University of Health Sciences

Kaunas, Lithuania

Instituto Português de Oncologia de Lisboa Francisco Gentil E.P.E.

Lisbon, Portugal

Imperial College Healthcare NHS Trust Hammersmith Hospital

London, United Kingdom