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RECRUITING
NCT07693972
NA

Probiotic Vs Zinc Chlorhexidine Zn/CHX Mouthwashes in Control Halitosis and Plaque in Fixed Orthodontic Patients

Sponsor: Sara M Almshhadany

View on ClinicalTrials.gov

Summary

This study aims to determine the effect of probiotics and Zn/CHx mouthwashes on plaque accumulation and halitosis in fixed orthodontic patients.

Key Details

Gender

All

Age Range

18 Years - 30 Years

Study Type

INTERVENTIONAL

Enrollment

60

Start Date

2025-12-31

Completion Date

2026-09-30

Last Updated

2026-07-09

Healthy Volunteers

Yes

Conditions

Interventions

OTHER

Probiotic (L. brevis CD2 lozenges)

Probiotic :composed of powerful strain of s.salivarius that preserve innate immune system of the main entry point of the body by taken on a regular basis and establish colonization of the throat and mouth which provide clinical care and support of nose, ear, mouth and throat health and provide fresh breath.

BEHAVIORAL

Zinc chlorhexidine mouth wash

Zinc chlorhexidine mouth wash (Zn/CHX) composed of CHX concentrated 0.025% with Zinc acetate 0.3 %, the low concentration of CHX to maintain optimal efficacy with lower incidence of side effects. Zn /CHX was chosen as the active control due to the fact the mixture of Zn salts with low concentration of CHX have shown superior and sustained intra-oral efficacy in managing intra oral halitosis in randomized clinical tria

Locations (1)

College of Dentistry

Baghdad, Alkargh, Iraq