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Metabolic Effects of Diet-Exercise Interventions in Obesity
Sponsor: Firat University
Summary
This study investigates the effects of different dietary strategies (ketogenic diet, intermittent fasting, and semi-vegetarian diet), alone or in combination with a structured home-based exercise program, on anthropometric, metabolic, and hormonal parameters in women with obesity. A total of 108 participants aged 19-45 years are allocated into nine groups, including control, exercise-only, diet-only, and combined intervention groups. Anthropometric outcomes (body weight, body mass index, and body fat percentage) and biochemical markers (glucose, insulin, adiponectin, IGF-1, irisin, and myostatin) are assessed at baseline and after a 6-week intervention period using bioelectrical impedance analysis and ELISA methods.
Official title: Metabolic Responses of Diet-Exercise Combinations in Women With Obesity: A Comparative Lifestyle Intervention Study With Different Diet Types
Key Details
Gender
FEMALE
Age Range
19 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
108
Start Date
2023-07-30
Completion Date
2024-01-12
Last Updated
2026-07-10
Healthy Volunteers
Yes
Conditions
Interventions
Home-Based Exercise Program
A 6-week structured home-based exercise program consisting of moderate-intensity activities designed for weight management and metabolic improvement.
Semi-Vegetarian Diet
A 6-week structured semi-vegetarian dietary protocol primarily based on plant foods with occasional inclusion of meat or fish, designed for caloric control and metabolic tracking.
Intermittent Fasting
A 6-week structured intermittent fasting protocol regulating specific eating and fasting windows each day to evaluate its effects on body composition and metabolic markers.
Ketogenic Diet
A 6-week structured ketogenic dietary protocol characterized by high-fat, adequate-protein, and very low-carbohydrate intake to induce nutritional ketosis.
Locations (1)
Fırat University Hospital
Elâzığ, Turkey (Türkiye)