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NCT07697417

Multimodal Prediction of Postoperative Prognosis After Partial Nephrectomy for Endophytic Renal Cell Carcinoma

Sponsor: Tianjin Medical University Second Hospital

View on ClinicalTrials.gov

Summary

This retrospective observational cohort study aims to develop and externally validate an imaging-clinical multimodal fusion model for predicting postoperative prognosis in patients with endophytic renal cell carcinoma undergoing partial nephrectomy. Preoperative computed tomography imaging features, three-dimensional reconstruction-derived tumor characteristics, radiomics features, and clinical variables will be integrated using machine learning and deep learning approaches. The primary objective is to evaluate whether the multimodal model improves prediction of postoperative prognostic outcomes compared with single-modality models based on clinical or imaging features alone.

Official title: Development and External Validation of an Imaging-Clinical Multimodal Fusion Model for Predicting Postoperative Prognosis After Partial Nephrectomy in Patients With Endophytic Renal Cell Carcinoma

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

406

Start Date

2026-01-01

Completion Date

2026-12-01

Last Updated

2026-07-13

Healthy Volunteers

No

Interventions

OTHER

Imaging-clinical multimodal prognostic modeling

Preoperative CT imaging features, radiomics features, three-dimensional reconstruction-derived features, and clinical variables will be retrospectively analyzed to develop and validate a multimodal model for predicting postoperative prognosis after partial nephrectomy. No intervention will be assigned to participants.

Locations (1)

Tianjin Medical University Second Hospital

Tianjin, Tianjin Municipality, China