Clinical Research Directory

Recovery and Quality of Life in Cervical Cancer Patients Using Vaginal Dilators After Radiotherapy

Sponsor: Chulabhorn Cancer Center

Summary

The goal of this longitudinal observational study is to understand the trajectory of Quality of Life (QoL) recovery in women with cervical cancer who have received definitive radiation therapy. The main questions it aims to answer are: Do functional domains, such as physical, role, and social functioning, show significant and sustained improvement over the 12 months following treatment? How does the burden of treatment-related symptoms, including fatigue, nausea, and cervical cancer-specific symptoms, resolve during the one-year recovery period? Researchers will analyze changes in QoL scores over time to identify which clinical factors-such as time elapsed since treatment and baseline disease stage-serve as the most significant predictors of a patient's overall well-being. Participants will: * Complete standardized Quality of Life assessments using the EORTC QLQ-C30 and the cervical cancer-specific QLQ-CX24 instruments. * Provide data at six specific intervals: baseline (pre-treatment) and at 1, 3, 6, 9, and 12 months post-radiotherapy. * Report on multiple functional scales, including physical, role, emotional, cognitive, and social status. * Monitor and report symptom levels for various issues such as fatigue, pain, nausea, and sexual/vaginal functioning.

Official title: Impact of Vaginal Dilator Use on Vaginal Morbidity and Quality of Life Following Definitive Radiation Therapy for Cervical Cancer.

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