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Selective Median Lobe Surgery Outcomes Study
Sponsor: Necmettin Erbakan University
Summary
This prospective multicenter observational cohort study will evaluate clinical outcomes after selective median lobe transurethral surgery for benign prostatic obstruction. Eligible men with lower urinary tract symptoms or urinary retention who are scheduled for selective median lobe-only TURP, HoLEP, or anatomical endoscopic enucleation as part of routine clinical care will be enrolled and followed after surgery. The study will collect preoperative clinical data, symptom scores, uroflowmetry, postvoid residual volume, prostate volume, intravesical prostatic protrusion measurements, cystoscopic anatomical findings, intraoperative variables, and postoperative outcomes. The primary outcome is composite clinical failure at 12 months. The main aim is to identify practical preoperative urology-based anatomical and functional predictors of clinical failure after selective median lobe surgery and to develop an exploratory prediction model that may help improve patient selection in future practice.
Official title: UNVEIL-BPO Median Lobe Study: An International Multicenter Evaluation of Selective Median Lobe Resection and Enucleation
Key Details
Gender
MALE
Age Range
45 Years - Any
Study Type
OBSERVATIONAL
Enrollment
420
Start Date
2026-09-01
Completion Date
2030-12-01
Last Updated
2026-07-13
Healthy Volunteers
No
Conditions
Interventions
Selective Median Lobe TURP
Selective transurethral resection of the median lobe or median component of the bladder outlet. The procedure is performed according to the treating surgeon's routine clinical practice and is not assigned by the study protocol.
Selective Median Lobe HoLEP/AEEP
Selective enucleation of the median lobe or median component of the bladder outlet using HoLEP or another anatomical endoscopic enucleation platform. The procedure is performed according to the treating surgeon's routine clinical practice and is not assigned by the study protocol.
Locations (2)
University of Health Sciences Türkiye, Van Training and Research Hospital
Van, Edremit, Turkey (Türkiye)
Necmettin Erbakan University, Meram Faculty of Medicine
Konya, Konya, Turkey (Türkiye)