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Assessment of Peridontal Inflamatuar Markers in MIH
Sponsor: Marmara University
Summary
The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal treatment due to gingivitis. The main questions it aims to answer are: Are the levels of periodontal inflammatory mediators in gingival crevicular fluid different between children with MIH and those without MIH? Is the presence and severity of MIH associated with clinical periodontal parameters and dentin hypersensitivity? Researchers will compare children with MIH to children without MIH to determine whether MIH is associated with changes in periodontal inflammatory mediator levels and periodontal clinical findings.
Official title: Investigation of Periodontal Inflammatory Mediators in Permanent Molars Affected by Molar-incisor Hypomineralization
Key Details
Gender
All
Age Range
8 Years - 13 Years
Study Type
OBSERVATIONAL
Enrollment
76
Start Date
2026-07-16
Completion Date
2027-11-01
Last Updated
2026-07-14
Healthy Volunteers
Yes
Conditions
Interventions
Initial periodontal treatment
DOS samples will be taken before and after treatment
Locations (1)
Marmara Üniversitesi Recep Tayyip Erdoğan Külliyesi Sağlık Yerleşkesi, Diş Hekimliği Fakültesi
Istanbul, MALTEPE, Turkey (Türkiye)