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NOT YET RECRUITING
NCT07701642

Assessment of Peridontal Inflamatuar Markers in MIH

Sponsor: Marmara University

View on ClinicalTrials.gov

Summary

The goal of this observational study is to investigate periodontal inflammatory mediators in systemically healthy children aged 8-13 years with and without molar-incisor hypomineralization (MIH) who require initial periodontal treatment due to gingivitis. The main questions it aims to answer are: Are the levels of periodontal inflammatory mediators in gingival crevicular fluid different between children with MIH and those without MIH? Is the presence and severity of MIH associated with clinical periodontal parameters and dentin hypersensitivity? Researchers will compare children with MIH to children without MIH to determine whether MIH is associated with changes in periodontal inflammatory mediator levels and periodontal clinical findings.

Official title: Investigation of Periodontal Inflammatory Mediators in Permanent Molars Affected by Molar-incisor Hypomineralization

Key Details

Gender

All

Age Range

8 Years - 13 Years

Study Type

OBSERVATIONAL

Enrollment

76

Start Date

2026-07-16

Completion Date

2027-11-01

Last Updated

2026-07-14

Healthy Volunteers

Yes

Interventions

PROCEDURE

Initial periodontal treatment

DOS samples will be taken before and after treatment

Locations (1)

Marmara Üniversitesi Recep Tayyip Erdoğan Külliyesi Sağlık Yerleşkesi, Diş Hekimliği Fakültesi

Istanbul, MALTEPE, Turkey (Türkiye)