Clinical Research Directory

Inclusion Criteria: * Individuals 16 to 40 years with molecular or biochemical confirmation of a urea cycle disorder. * Healthy individuals will serve as an age and sex matched comparison group. Active driver's license for at least 6 months * Read and understand English. as the tasks have not been validated in other languages * IQ \>=70. Exclusion Criteria: * Skin disease that affects the scalp * Past or present vascular disease * Head trauma with loss of consciousness in the last year or evidence of cognitive impairment due to and persisting after head trauma * Motor movement disorder which may cause excessive movement or impede use of the steering wheel and/or pedal * Premature birth or birth before 32 weeks of gestation * The participant is taking a stimulant or antidepressant * Allergy to any component of the device, although expected to be rare * History of psychosis * Self-reported motion or cyber sickness * Self-reported illicit substance use * Vision disorder