Clinical Research Directory

Inclusion Criteria: * Adults aged 18 years or older. * Diagnosis of polytrauma, defined as traumatic injuries involving two or more anatomical regions. * Injury Severity Score (ISS) ≥16. * Hospital admission within 48 hours after injury. * Requirement for acute pain management during hospital treatment. * Receipt of at least one ultrasound-guided peripheral nerve block and/or continuous peripheral nerve catheter as part of routine clinical care. * Ability to collect clinical data on regional anesthesia procedures, analgesic use, pain assessment, and early recovery outcomes. * Written informed consent provided by the patient or legally authorized representative, according to local regulations. Exclusion Criteria: * Age younger than 18 years. * Isolated single-system injury without polytrauma. ISS \<16. * Expected survival less than 24 hours after admission. * Severe traumatic brain injury or impaired consciousness preventing reliable pain and functional assessment, unless validated behavioral pain scales can be used. * Known allergy or contraindication to local anesthetics. * Pre-existing severe neuromuscular disease affecting motor function assessment. * Chronic opioid therapy before injury. * Pregnancy. * Enrollment in another interventional trial that may affect pain management or functional recovery outcomes. * Missing essential data required for assessment of Regional Anesthesia Burden.