Clinical Research Directory

Inclusion Criteria: * Male and female children ages 7 through 17 years of age at the start of the Screening Period. * Participants with a known history of allergic reactions with an active prescription for epinephrine, and who (in the judgement of the investigator) are at high risk for serious allergic reactions (e.g., anaphylaxis). * Participant has a body weight ≥30 kg (66 lbs). * Participant is within the 5th and 95th percentiles, inclusive, for weight by age (according to CDC growth charts). Exclusion Criteria: * Any current or past medical conditions such as significant systemic diseases that, in the investigator's opinion, might significantly affect pharmacodynamic responses to DESF. * Concurrent clinically significant cardiovascular, hematological, renal, neurologic, hepatic, endocrine, psychiatric, or malignant diseases. * Known intolerance or hypersensitivity to any component of DESF. * Participant has a disease or condition known to interfere with the absorption, distribution, metabolism, or excretion of DESF. * Positive urine drug screen, saliva alcohol test, or urine cotinine test at Screening or prior to administration of DESF on Study Day 1. * Participant has participated in any clinical investigation within the 30 days prior to the planned administration of DESF on Study Day 1.