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Assessment of Retinal Microcirculation in Patients With Type 1 Diabetes Mellitus
Sponsor: University of Athens
Summary
Type 1 diabetes mellitus (T1DM) is associated with an increased lifetime risk of developing diabetic retinopathy, a leading cause of visual impairment among working-age adults worldwide. Retinal assessment plays a pivotal role in the management of patients with T1DM, as the retina provides a unique, non-invasive window into the body's microvascular circulation. Early detection of retinal abnormalities is essential because structural and microvascular changes may develop years before the onset of vision-threatening diabetic retinopathy or visual symptoms. Contemporary retinal imaging techniques, enable the quantitative evaluation of retinal microvasculature allowing the identification of subclinical retinal damage.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
100
Start Date
2025-06-01
Completion Date
2026-09-30
Last Updated
2026-07-15
Healthy Volunteers
No
Conditions
Interventions
Optical Coherence Tomography Angiography (OCTA)
A non-invasive retinal imaging technique that provides high-resolution visualization and quantitative assessment of the retinal and choroidal microvasculature, including vessel density and the foveal avascular zone, without the use of intravenous dye.
Locations (1)
2nd Department of Ophthalmology, Attikon University Hospital, National and Kapodistrian University of Athens
Athens, Greece