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COMPLETED
NCT07706036
NA

Naproxen and Lidocaine Gel Combination for Rib Fracture

Sponsor: Ankara City Hospital Bilkent

View on ClinicalTrials.gov

Summary

This study evaluates whether adding a topical gel containing naproxen and lidocaine to routine intravenous analgesic treatment improves pain relief in adults with isolated traumatic rib fractures presenting to the emergency department. Participants are randomly allocated to receive either standard intravenous dexketoprofen alone or dexketoprofen combined with topical naproxen-lidocaine gel. Pain intensity is measured repeatedly during the first hour after treatment using the Numerical Rating Scale (NRS). The study also examines the need for additional rescue analgesia and monitors treatment-related adverse events to determine the effectiveness and safety of this multimodal analgesic strategy.

Official title: Analgesic Efficacy of a Naproxen and Lidocaine Gel Combination in Patients With Traumatic Rib Fractures: A Randomized Controlled Trial

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

110

Start Date

2024-01-01

Completion Date

2024-07-02

Last Updated

2026-07-20

Healthy Volunteers

No

Interventions

DRUG

A gel combination containing 10% naproxen and 5% lidocaine

Approximately 10 grams of a gel combination containing 10% naproxen and 5% lidocaine to the rib fracture site, covering both the upper and lower ribs

DRUG

Dexketoprofen trometamol 50 mg IV

Dexketoprofen at a dose of 50 mg, dissolved in 150 ml of 0.9% NaCl solution and administered intravenously via rapid infusion over 15 minutes

Locations (1)

Ankara Bilkent City Hospital; Department of Emergency Medicine

Ankara, Çankaya, Turkey (Türkiye)