Clinical Research Directory
Browse clinical research sites, groups, and studies.
Permissive Hyperthermia in Acute Brain Injury
Sponsor: Odense University Hospital
Summary
The purpose of this pilot study is to find out whether it is possible to work together with the body's own reactions, where the temperature goes up (fever), in a safe and controlled way. The main question to answer is: Is it practical and safe to allow higher body temperature (up to 39.5°C) as part of the treatment for critically ill patients with brain injury? Patients with acute brain injury will be Placed in one of two groups: one where fever is treated to keep the temperature below 37.5°C, and one where fever is allowed up to 39.5°C.
Official title: Permissive Hyperthermia in Traumatic Brain Injury and Acute Vascular Brain Injury
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2026-04-25
Completion Date
2028-02-01
Last Updated
2026-07-16
Healthy Volunteers
No
Conditions
Interventions
Temperature < 39,5
Allowing temperature up to 39,5 in patients with acute brain injury
Temperature <37.5
Standard care of temperature
Locations (1)
Neurointensiv care
Odense C, Denmark