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Role of Urine PH in Shock Wave Lithotripsy Outcomes in Renal Stone Disease
Sponsor: Benha University
Summary
urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients. * Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones \< 2 cm. * Hypothesis: Urine pH might influence SWL success and could be manipulated pre-procedure. Aim of the work is to evaluate the role urine pH on the outcomes of shock wave lithotripsy in renal stones. patients and methods The study will be conducted over 146 patients( with single renal stone \< 2 cm) in Urology department of Banha university Hopitals from Dec 2025 till Dec 2026. Exclusions: patients on pH altering drugs, multiple stones,stents. Procedure: SWL Siemens Lithoscope up to 3 sessions per patient. Data collected : Age, BMI, urine pH, specific gravity(SG), stone size, location, Hounsfield unit(HU), skin to stone distance (SSD). Analysis Chi-square\& t-test; significance at p\<0.05. Results Will be tabulated and statistically analyzed
Official title: EFFECT of PH on Outcomes of ESWL in Renal Stones
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
146
Start Date
2026-01-20
Completion Date
2026-10-31
Last Updated
2026-07-20
Healthy Volunteers
Yes
Conditions
Interventions
Shock Wave Iithotripsy
ESWL in renal stone disease
Extracorporeal shock wave lithotripsy
The procedures utilized advanced lithotripsy systems, specifically the Siemens Lithoskop and a piezoelectric lithotripter (Piezolith 3000 Plus, Richard Wolf, Germany) equipped with direct-focusing shockwave technology and triple focus size localization capabilities (F1 =2 mm, F2 =4 mm, F3 =8 mm). During the procedure, an integrated ultrasound device was primarily used to locate and continuously monitor the targeted stone in real-time, significantly minimizing radiation exposure. Fluoroscopy was employed only briefly and strictly to confirm the anatomical position and radiolucency of lower calyceal stones. The procedural parameters were standardized across the cohort: the shockwave delivery rate was set at 90 pulses per minute, with a strict safety cap of 3000 shockwaves per session. The mechanical fragmentation strategy utilized a progressive focusing technique. Treatment commenced with the smallest focal size (F1) to safely initiate stone breakdown.
Locations (1)
Benha University Hospitals
Banhā, Benha, Egypt