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Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+)
Sponsor: University of California, Irvine
Summary
Lung cancer screening (LCS) with low-dose computed tomography (LDCT) can reduce the risk of dying from lung cancer, but many people who are eligible for screening do not receive it. The purpose of the Empower LCS/Call+ study is to evaluate new strategies to improve lung cancer screening among adults who are eligible for screening based on current U.S. Preventive Services Task Force (USPSTF) guidelines. This pilot randomized controlled trial will enroll approximately 80 participants from UC Irvine Health and Emory Healthcare. Participants will be randomly assigned to receive either enhanced usual care or the Empower LCS/Call+ intervention. The intervention includes educational materials, reminders for patients and primary care providers, and information about financial and community resources when appropriate. Participants who do not complete lung cancer screening after the initial intervention may receive additional telephone-based navigation through the Call+ program to help identify and address barriers to screening and help with scheduling. Participants will complete a baseline survey and follow-up surveys at 4 and 8 months, and researchers will review electronic health record information to determine whether lung cancer screening was discussed, ordered, and completed. Some participants will also be invited to complete a one-time interview about their experiences with the study. The results of this study will help determine the feasibility, acceptability, and preliminary effectiveness of the Empower LCS/Call+ intervention and will inform future efforts to improve equitable access to lung cancer screening.
Official title: Empowering Patients' Lung Cancer Screening Uptake (Empower LCS/Call+): A Multi-Site Pilot Randomized Controlled Trial
Key Details
Gender
All
Age Range
50 Years - 80 Years
Study Type
INTERVENTIONAL
Enrollment
80
Start Date
2026-09-01
Completion Date
2028-12
Last Updated
2026-07-22
Healthy Volunteers
No
Interventions
Empower LCS
Empower LCS consists of (1) a lung cancer screening decision aid, (2) primary care provider notification of patients' eligibility for lung cancer screening, (3) patient text reminders to discuss lung cancer screening with their primary care provider, and (4) tailored support materials including financial education and national/local resources for patients who screen positive for health-related social needs.
Call+ Telephone Navigation
Participants who do not complete lung cancer screening by approximately 4 months after randomization will receive the Call+, a telephone-based navigation intervention delivered by a lay navigator to identify and address barriers to screening, facilitate scheduling, and connect participants with available resources.
Usual Care
Usual care
Education
One-page educational material about benefits and risks of lung cancer screening
Locations (57)
UCI Health Family Health Center - Anaheim
Anaheim, California, United States
UCI Health - Costa Mesa
Costa Mesa, California, United States
CHAO Family Comprehensive Cancer Center- Irvine
Irvine, California, United States
UCI Health Gottschalk Medical Plaza
Irvine, California, United States
UCI Health - Laguna Hills
Laguna Hills, California, United States
UCI Health - Newport Beach MacArthur
Newport Beach, California, United States
Primary Care & Internal Medicine Services
Orange, California, United States
UCI Chao Family Comprehensive Cancer Center
Orange, California, United States
UCI Health SeniorHealth Center -Pavillion 4
Orange, California, United States
UCI Medical Center, Pavilion 3
Orange, California, United States
UCI Health Family Health Center - Santa Ana
Santa Ana, California, United States
UCI Health - Tustin
Tustin, California, United States
UCI Health - Yorba Linda
Yorba Linda, California, United States
Emory at Avalon - Primary Care
Alpharetta, Georgia, United States
Emory Clinic at Old Fourth Ward
Atlanta, Georgia, United States
Emory Clinic at Midtown
Atlanta, Georgia, United States
Emory at Peachtree Hills - Primary Care
Atlanta, Georgia, United States
Emory Clinic at 1365 Clifton Road - Primary Care
Atlanta, Georgia, United States
Emory Clinic at 1525 Clifton Road - Primary Care
Atlanta, Georgia, United States
Emory at Toco Hills - Primary Care
Atlanta, Georgia, United States
Emory Gastroenterology
Atlanta, Georgia, United States
Emory at Northlake - Primary Care
Atlanta, Georgia, United States
Emory at Buford - Primary Care
Buford, Georgia, United States
Emory at Decatur - Primary Care (Irvin Court)
Decatur, Georgia, United States
Emory at Decatur - Primary Care (Scott Boulevard)
Decatur, Georgia, United States
Emory Clinic Downtown Decatur
Decatur, Georgia, United States
Emory at Decatur - Primary Care
Decatur, Georgia, United States
Emory at Oak Grove - Primary Care
Decatur, Georgia, United States
Emory Clinic at Decatur - Primary Care
Decatur, Georgia, United States
Emory at Flat Shoals - Primary Care
Decatur, Georgia, United States
Emory at Duluth
Duluth, Georgia, United States
Emory at Sugarloaf - Primary Care
Duluth, Georgia, United States
Emory at Dunwoody
Dunwoody, Georgia, United States
Emory Clinic at Saint Joseph's
Dunwoody, Georgia, United States
Emory at Findley Road
Johns Creek, Georgia, United States
Emory at Spivey Station - Primary Care
Jonesboro, Georgia, United States
Emory at LaGrange - Smith Street - Primary Care
La Grange, Georgia, United States
Emory at LaGrange - Davis Road
La Grange, Georgia, United States
Emory at Beaver Ruin - Primary Care
Lilburn, Georgia, United States
Emory at Mountain Park - Primary Care
Lilburn, Georgia, United States
Emory at Hillandale Family Medicine
Lithonia, Georgia, United States
Emory at Miller Grove - Primary Care
Lithonia, Georgia, United States
Emory Clinic at Lithonia - Primary Care
Lithonia, Georgia, United States
Emory at East Cobb - Primary Care
Marietta, Georgia, United States
Emory at Peachtree City - Primary Care
Peachtree City, Georgia, United States
Emory at Sharpsburg
Sharpsburg, Georgia, United States
Emory at Belmont - Primary Care
Smyrna, Georgia, United States
Emory at Snellville - Primary Care (Lenora Church Road)
Snellville, Georgia, United States
Emory at Snellville - Primary Care (Oak Road)
Snellville, Georgia, United States
Emory at Snellville Primary Care (Presidential Circle)
Snellville, Georgia, United States
Emory at Centerville - Primary Care
Snellville, Georgia, United States
Emory at Eagles Landing Primary Care
Stockbridge, Georgia, United States
Emory at Stone Mountain - Primary Care
Stone Mountain, Georgia, United States
Emory at Rockbridge Primary Care & Nephrology
Stone Mountain, Georgia, United States
Emory at Tucker - Primary Care (1459 Montreal Road)
Tucker, Georgia, United States
Pavilion Family Medicine Center
Warner Robins, Georgia, United States
Emory at West Point
West Point, Georgia, United States