Clinical Research Directory
Browse clinical research sites, groups, and studies.
PRIMARY-HF: Heart Failure Screening in Primary Care Using Point-of- Care
Sponsor: Universidade do Porto
Summary
The goal of this clinical trial is to evaluate whether the use of NT-proBNP testing and point-of-care ultrasound (POCUS) can improve the diagnosis and management of heart failure in adults aged 50 years or older with suspected heart failure or cardiovascular risk factors in primary care settings. The main questions it aims to answer are: * Does the use of NT-proBNP and/or POCUS increase the rate of new heart failure diagnoses compared with standard care? * Does this approach support earlier initiation of guideline-directed medical therapy and improve patients' quality of life? Researchers will compare standard care alone with standard care combined with NT-proBNP testing, POCUS, or both, to assess their impact on diagnosis and management of heart failure. Participants will: * Be randomly assigned to one of four groups (standard care, NT-proBNP, POCUS, or both). * Undergo clinical evaluation for heart failure according to their assigned group. * Be followed for 12 months with periodic assessments of quality of life and treatment adherence.
Official title: PRIMARY-HF: Diagnóstico de Insuficiência Cardíaca em Cuidados de Saúde Primários Utilizando Ecografia Point-of-Care e Péptidos Natriuréticos
Key Details
Gender
All
Age Range
49 Years - Any
Study Type
INTERVENTIONAL
Enrollment
160
Start Date
2026-03-23
Completion Date
2027-07
Last Updated
2026-07-17
Healthy Volunteers
No
Conditions
Interventions
NT-proBNP testing
Measurement of N-terminal pro-B-type natriuretic peptide (NT-proBNP) levels in blood as part of the diagnostic evaluation for suspected heart failure in primary care.
Cardiac Point-of-Care Ultrasound (POCUS)
Cardiac point-of-care ultrasound performed by trained primary care physicians to assess cardiac structure and function as part of the diagnostic evaluation for suspected heart failure.
standard of care
Usual clinical evaluation and management in primary care according to standard practice, without additional diagnostic interventions specified in the study.
Locations (4)
Unidade de Saúde Familiar Conde da Lousã
Amadora, Portugal
Unidade de Saúde Familiar do Parque
Lisbon, Portugal
Unidade de Saúde Familiar Rodrigues Miguéis
Lisbon, Portugal
Unidade de Saúde Familiar Garcia Orta
Porto, Portugal