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A Study of V132 in Healthy Older Participants (V132-001)
Sponsor: Merck Sharp & Dohme LLC
Summary
The goal of this study is to learn about the safety and immune response to the V132 vaccine in healthy older adults.
Official title: A Phase 1, Randomized, Double-Blind, Comparator-Controlled Dose-Escalation Study to Evaluate the Safety, Tolerability, and Immunogenicity of V132 in Healthy Older Participants
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
280
Start Date
2026-08-12
Completion Date
2028-06-21
Last Updated
2026-10-05
Healthy Volunteers
Yes
Conditions
Interventions
V132 Formulation 1
Experimental
V132 Formulation 2
Experimental
V132 Formulation 3
Experimental
PREVNAR 20™
Active Comparator
CAPVAXIVE™
Active Comparator
Locations (10)
Anaheim Clinical Trials ( Site 0006)
Anaheim, California, United States
Velocity Clinical Research, Hallandale Beach ( Site 0003)
Hallandale, Florida, United States
Research Centers of America ( Hollywood ) ( Site 0009)
Hollywood, Florida, United States
QPS-MRA, LLC-Early Phase ( Site 0001)
South Miami, Florida, United States
Bio-Kinetic Clinical Applications, LLC dba QPS-MO ( Site 0002)
Springfield, Missouri, United States
Velocity Clinical Research Lincoln ( Site 0007)
Lincoln, Nebraska, United States
Velocity Clinical Research, Omaha ( Site 0008)
Omaha, Nebraska, United States
Remington-Davis, Inc. ( Site 0005)
Columbus, Ohio, United States
Velocity Clinical Research, Providence ( Site 0010)
East Greenwich, Rhode Island, United States
University of Texas Medical Branch ( Site 0004)
League City, Texas, United States