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NOT YET RECRUITING
NCT07712575
PHASE1
A Study of V132 in Healthy Older Participants (V132-001)
Sponsor: Merck Sharp & Dohme LLC
View on ClinicalTrials.gov
Summary
The goal of this study is to learn about the safety and immune response to the V132 vaccine in healthy older adults.
Official title: A Phase 1, Randomized, Double-Blind, Comparator-Controlled Dose-Escalation Study to Evaluate the Safety, Tolerability, and Immunogenicity of V132 in Healthy Older Participants
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
280
Start Date
2026-08-17
Completion Date
2028-06-21
Last Updated
2026-07-17
Healthy Volunteers
Yes
Conditions
Interventions
BIOLOGICAL
V132 Formulation 1
Experimental
BIOLOGICAL
V132 Formulation 2
Experimental
BIOLOGICAL
V132 Formulation 3
Experimental
BIOLOGICAL
PREVNAR 20™
Active Comparator
BIOLOGICAL
CAPVAXIVE™
Active Comparator