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SALVAGE Trial (Safety And cLinical Value of AutoloGous rEinfusion)
Sponsor: Mayo Clinic
Summary
The investigator hypothesizes intraoperative salvaged red blood cells are a poor substitute for allogenic packed red blood cell transfusions. In addition to providing inadequate resuscitation, salvaged red blood cells can increase the rate of complications, including postoperative electrolyte abnormalities, thrombocytopenia, anemia, and coagulopathy.
Official title: SALVAGE Trial (Safety And cLinical Value of AutoloGous rEinfusion): A Multicenter, Randomized, Open-Label, Parallel-Group Trial Comparing Intraoperative Cell Salvage Versus No Cell Salvage in Adult Spinal Deformity Surgery
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
146
Start Date
2026-11-01
Completion Date
2029-08-01
Last Updated
2026-09-11
Healthy Volunteers
No
Conditions
Interventions
Cell Saver
Using Cell Saver during surgery