Clinical Research Directory

Recontrast and Renal Outcomes in Patients With Pre-Existing Renal Dysfunction

Sponsor: Cairo University

Summary

Aim of study: The renal impact of repeated iodinated contrast exposure in critically ill patients with pre-existing renal impairment Methods: A prospective observational cohort study included 112 critically ill patients admitted to the intensive care units of Cairo University hospitals with baseline estimated glomerular filtration rate (eGFR) \<90 mL/min/1.73 m² who underwent one or two intravascular iodinated contrast administrations. Hemodynamically unstable patients were excluded. Patients were systematically followed to evaluate both short- and long-term renal outcomes. Serum creatinine, eGFR, urine output, contrast-associated acute kidney injury (CA-AKI), chronic kidney disease (CKD) progression and dialysis requirement were assessed after each exposure and during 6 months follow-up. Logistic regression analysis was performed.

Official title: Repeated Contrast Exposure and Kidney Outcomes in Critically Ill Patients With Pre-Existing Renal Dysfunction: A Prospective Cohort Study

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