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COMPLETED
NCT07714382

Survival Outcomes of Residual Disease in Triple-Negative Breast Cancer

Sponsor: Sohag University

View on ClinicalTrials.gov

Summary

Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer associated with a poor prognosis. Although neoadjuvant therapy improves outcomes in patients who achieve a pathological complete response, the presence of residual disease after treatment remains associated with an increased risk of recurrence and death. This retrospective cohort study aims to evaluate the survival outcomes of patients with residual disease following neoadjuvant therapy for TNBC and to assess the association between clinicopathological characteristics and survival outcomes, including disease-free survival and overall survival

Official title: Survival Outcomes of Residual Disease in Patients With Triple-Negative Breast Cancer Following Neoadjuvant Therapy: A Retrospective Cohort Study

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

100

Start Date

2026-05-01

Completion Date

2026-07-01

Last Updated

2026-07-20

Healthy Volunteers

Not specified

Interventions

PROCEDURE

Chemo-radiotherapy alone

Chemo and radiotherapy before surgery

OTHER

Not applicable- observational study

Not applicable. This is a retrospective observational cohort study. No study intervention is administered. Data will be collected retrospectively from patients' medical records, and all treatments were provided as part of routine clinical care.

Locations (1)

Sohag university

Sohag, Egypt