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RECRUITING
NCT07715188
NA

Low Dose Radiotherapy for Osteoarthritis

Sponsor: Abramson Cancer Center at Penn Medicine

View on ClinicalTrials.gov

Summary

This single institution, multi-site, single arm prospective study will enroll patients with a history of OA and assess changes in pain and function after treatment with LDRT as measured by patient-reported outcomes.

Official title: A Prospective Study of Low Dose Radiotherapy for Osteoarthritis

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

113

Start Date

2026-06-24

Completion Date

2029-06

Last Updated

2026-07-20

Healthy Volunteers

No

Conditions

Interventions

RADIATION

Low Dose Radiation Therapy

Participants will complete study intervention which consists of the BPI-SF, PROMIS Global v1.2, UEFI (for those with joint pain of the upper extremity) and/or LEFS (for those joint pain of the lower extremity) at baseline, 3-month and 1-year follow-up following 1 or 2 courses of standard of care LDRT.

Locations (2)

Penn Presbyterian Medical Center

Philadelphia, Pennsylvania, United States

Perelman Center for Advanced Medicine

Philadelphia, Pennsylvania, United States