Clinical Research Directory
Browse clinical research sites, groups, and studies.
Vestibular Perception Gates Autonomic Responses to Sinusoidal Galvanic Vestibular Stimulation
Sponsor: Al-Farabi Kazakh National University
Summary
Brief Summary This randomized, double-blind, sham-controlled clinical trial is designed to investigate whether repeated sinusoidal galvanic vestibular stimulation (GVS) influences cardiac autonomic regulation in healthy adults during their routine occupational activities, and to determine whether these effects depend on subjective vestibular perception (dizziness) experienced during stimulation. The main questions it aims to answer are: Does repeated sinusoidal GVS alter heart rate variability (HRV) in healthy adults during their normal work activities? Do autonomic responses to GVS depend on the subjective intensity of dizziness experienced during stimulation? Does repeated GVS affect psycho-emotional well-being, including depressive and anxiety symptoms? Researchers will compare active GVS to sham stimulation to see if active stimulation produces measurable changes in cardiac autonomic regulation and whether these changes differ between participants reporting stronger versus minimal dizziness. Participants will undergo baseline assessment, complete four consecutive daily sessions of active or sham GVS, and undergo post-intervention assessment. Autonomic responses will be assessed using multiple HRV indices.
Official title: Effects of Galvanic Vestibular Stimulation on Heart Rate Variability
Key Details
Gender
All
Age Range
18 Years - 49 Years
Study Type
INTERVENTIONAL
Enrollment
56
Start Date
2021-11-30
Completion Date
2022-05-13
Last Updated
2026-07-20
Healthy Volunteers
Yes
Conditions
Interventions
Galvanic Vestibular Stimulation (GVS) using BrainPatch device
Sinusoidal galvanic vestibular stimulation delivered via bilateral mastoid electrodes using the portable BrainPatch device. Stimulation parameters: 0.1 Hz sinusoidal waveform, peak current 0.62 mA, administered for 6 minutes per session with participants seated, eyes closed, and listening to relaxing meditative music.
Locations (2)
JSC "Kazakhtelecom"
Almaty, Kazakhstan
Al-Farabi Kazakh National University
Almaty, Kazakhstan