Clinical Research Directory
Browse clinical research sites, groups, and studies.
Assessment of Endocrine and Metabolic Late Effects After Childhood Brain Tumor Treatment
Sponsor: Institute of Oncology Ljubljana
Summary
This prospective, single-group interventional study evaluates endocrine and metabolic late effects in survivors of primary brain tumors treated during childhood. According to the study protocol, participants were prospectively assigned to undergo the Study-Specific Endocrine and Metabolic Late-Effects Assessment. The assessment included anthropometric measurements, repeated blood pressure measurements, clinical endocrine evaluation, fasting laboratory testing, and protocol-defined bone and vascular assessments. The purpose of the study was to identify the frequency and severity of endocrine and metabolic late effects and to evaluate their associations with tumor characteristics, previous cancer treatment, age at diagnosis, and physical functioning.
Official title: Late Endocrine and Metabolic Consequences of Treatment of Primary Brain Tumors in Childhood
Key Details
Gender
All
Age Range
5 Years - 35 Years
Study Type
INTERVENTIONAL
Enrollment
12
Start Date
2023-07-03
Completion Date
2025-12-31
Last Updated
2026-08-13
Healthy Volunteers
No
Interventions
Study-Specific Endocrine and Metabolic Late-Effects Assessment
According to the study protocol, participants underwent a study-specific assessment to identify endocrine and metabolic late effects after treatment of a primary brain tumor during childhood. The assessment included anthropometric measurements, repeated blood pressure measurements, clinical assessment of endocrine and pubertal status, and fasting laboratory testing of endocrine and metabolic markers. Vascular assessment included measurement of carotid intima-media thickness. Bone mineral density, body composition, and pulse wave velocity assessments were performed or arranged according to the protocol when the relevant results were not already available.
Locations (1)
Institute of Oncology Ljubljana
Ljubljana, Slovenia