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NCT07716774

SGLT-2 Inhibitors and Lower Urinary Tract Symptoms

Sponsor: Marmara University

View on ClinicalTrials.gov

Summary

This prospective observational study aims to evaluate the effects of sodium-glucose cotransporter 2 (SGLT-2) inhibitors on lower urinary tract symptoms (LUTS) in patients with type 2 diabetes mellitus. Patients who are newly initiated on SGLT-2 inhibitor therapy as part of routine clinical care will be evaluated at baseline and after one month using a 3-day bladder diary and the Overactive Bladder Questionnaire (OAB-v8). Changes in storage symptoms, including urinary frequency, urgency, nocturia, and urinary incontinence, will be assessed to better characterize the impact of SGLT-2 inhibitor therapy on LUTS.

Official title: Effects of Sodium-Glucose Cotransporter 2 Inhibitors on Lower Urinary Tract Symptoms

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

OBSERVATIONAL

Enrollment

40

Start Date

2026-07-01

Completion Date

2026-12-01

Last Updated

2026-07-21

Healthy Volunteers

Yes

Interventions

OTHER

No Intervention: Observational Cohort

No Intervention: Observational Cohort

Locations (1)

Marmara University School of Medicine Urology Department

Istanbul, Pendik, Turkey (Türkiye)