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Evaluation of The Effect of Injectable Platelet-rich Fibrin With Collagen Membrane in Miller Class II Gingival Recession Coverage
Sponsor: Tanta University
Summary
This study aims to evaluate the effect of injectable Platelet-Rich Fibrin (i-PRF) in combination with collagen membrane in the treatment of Miller Class II gingival recession. Gingival recession is a common periodontal condition characterized by apical displacement of the gingival margin, which may lead to aesthetic concerns, root hypersensitivity, and increased risk of root caries. The study will include patients diagnosed with Miller Class II gingival recession. Participants will be treated using a regenerative periodontal surgical approach involving coronally advanced flap combined with injectable platelet-rich fibrin and collagen membrane. Clinical parameters such as recession depth, clinical attachment level, and keratinized tissue width will be evaluated before and after treatment at specific follow-up intervals. The objective is to compare the effectiveness of this combined regenerative approach in improving root coverage and soft tissue healing, and to assess its potential benefits in periodontal regeneration and esthetic outcomes.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
20
Start Date
2024-02-24
Completion Date
2026-01-12
Last Updated
2026-07-28
Healthy Volunteers
No
Conditions
Interventions
Group (1)
Application of injectable platelet -rich fibrin (I-PRF) in combination with a collagen membrane during the surgical procedure to enhance soft and hard tissue healing
Group 2
coronally advanced flap surgery combined with a subepithelial connective tissue graft for the treatment of gingival recession defects
Locations (1)
Faculty of dentistry ,Tanta university
Tanta, Gharbia Governorate, Egypt