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Microneedling vs. 5-Fluorouracil or Steroid Injections for Hypertrophic Scars and Keloids
Sponsor: Alexandria University
Summary
The goal of this clinical trial is to learn about the efficacy and safety of microneedling-assisted 5-fluorouracil delivery in comparison with intralesional 5-fluorouracil, intralesional corticosteroid, and microneedling with saline for the treatment of pathological scars.
Official title: Microneedling With 5-Fluorouracil Versus Intralesional 5-Fluorouracil or Corticosteroids for Hypertrophic Scars and Keloids
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2023-01-12
Completion Date
2025-03-08
Last Updated
2026-07-21
Healthy Volunteers
No
Conditions
Interventions
Microneedling with 5-Fluorouracil
Undiluted 5-FU was applied topically after microneedling
Intralesional 5-fluorouracil
undiluted 5-fluorouracil was applied topically
Intralesional Triamcinolone Acetonide
Triamcinolone acetonide was administered intralesionally
Microneedling With saline
saline was applied after microneedling
Locations (1)
alexandria University Hospital
Alexandria, Egypt