Clinical Research Directory

Inclusion criteria for patients with Alzheimer's disease (AD): * Age between 50 and 90 years. * Diagnosis of Alzheimer's disease according to established diagnostic criteria. * Mini-Mental State Examination (MMSE) score between 18 and 24. * Stable pharmacological treatment for at least 3 months before enrolment. * Ability and willingness to provide written informed consent. Inclusion criteria for caregivers: * Age ≥18 years. * Availability to assist the patient throughout the study. * Ability and willingness to provide written informed consent. Exclusion criteria for patients with Alzheimer's disease (AD): * Refusal or inability to provide written informed consent. * History of psychiatric disorders. * Significant cerebrovascular disease. * Severe visual or hearing impairment that could interfere with study procedures. * Psychosis. * Major depressive disorder. * Alcohol or substance abuse. * Use of psychotropic medications that may interfere with neuropsychological assessment or study treatment. * Concurrent participation in another interventional pharmacological clinical trial. * Any contraindication to undergoing EEG recording. Exclusion criteria for caregivers: * Refusal or inability to provide written informed consent. * History of psychiatric disorders. * Major depressive disorder. * Alcohol or substance abuse. * Use of psychotropic medications that may interfere with neuropsychological assessment.