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Topical Oxygen Therapy for BRONJ
Sponsor: Mansoura University
Summary
A randomized clinical trial comparing Blue®m oral gel and autologous PRF membrane as adjuncts to surgical debridement in BRONJ/MRONJ patients.
Official title: Efficacy of Topically Applied Oxygen-Based Therapy Versus Platelet-Rich Fibrin for Medication-Related Osteonecrosis of the Jaws: A Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
36
Start Date
2026-04-01
Completion Date
2026-09
Last Updated
2026-07-24
Healthy Volunteers
No
Conditions
Interventions
Topical Blue®m application
Intraoperative application of Blue®m oral gel to the debrided surgical site before primary closure
PRF membrane placement
Intraoperative placement of an autologous PRF membrane over the debrided surgical site before flap closure.
Locations (1)
Faculty of Dentistry Mansoura University
Al Mansurah, Egypt