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NOT YET RECRUITING
NCT07725588
PHASE2

RCT of Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain

Sponsor: VA Office of Research and Development

View on ClinicalTrials.gov

Summary

Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions should address the unique needs of Veterans with PTSD/CP. Mantram Repetition Program (MRP), a meditation-based program, appears well-suited to address these high-priority VA needs. MRP has established effectiveness for treatment of PTSD, is broadly acceptable, can be learned quickly and applied flexibly. However, rigorous testing is needed for pain-related outcomes among a PTSD/CP population. The proposed study will include a randomized controlled trial comparing the efficacy of MRP for PTSD/CP to Health Education while Living with Pain among a sample of 170 Veterans with comorbid PTSD/CP. The primary outcomes will be PTSD symptoms and pain interference. Results from this study will directly inform patient care among the nearly 4% of Veterans with PTSD/CP.

Official title: Randomized Controlled Trial of Mantram Repetition Program Versus Health and Wellness Psychoeducation for Veterans With Comorbid Posttraumatic Stress Disorder and Chronic Pain

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

170

Start Date

2027-04-01

Completion Date

2030-09-30

Last Updated

2026-07-24

Healthy Volunteers

No

Interventions

BEHAVIORAL

Mantram Repetition Program for PTSD + Pain

manualized Mantram Repetition Program adapted for Veterans with PTSD and chronic pain

BEHAVIORAL

Health Education while Living with Pain

manualized health and wellness psychoeducation and discussion group

Locations (1)

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States