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RCT of Mantram Repetition Versus Health Education for Veterans With PTSD and Chronic Pain
Sponsor: VA Office of Research and Development
Summary
Approximately 450,000 Veterans Health Administration service users have both posttraumatic stress disorder (PTSD) and chronic pain (CP); treatments that efficiently target both PTSD and CP are limited, and new interventions should address the unique needs of Veterans with PTSD/CP. Mantram Repetition Program (MRP), a meditation-based program, appears well-suited to address these high-priority VA needs. MRP has established effectiveness for treatment of PTSD, is broadly acceptable, can be learned quickly and applied flexibly. However, rigorous testing is needed for pain-related outcomes among a PTSD/CP population. The proposed study will include a randomized controlled trial comparing the efficacy of MRP for PTSD/CP to Health Education while Living with Pain among a sample of 170 Veterans with comorbid PTSD/CP. The primary outcomes will be PTSD symptoms and pain interference. Results from this study will directly inform patient care among the nearly 4% of Veterans with PTSD/CP.
Official title: Randomized Controlled Trial of Mantram Repetition Program Versus Health and Wellness Psychoeducation for Veterans With Comorbid Posttraumatic Stress Disorder and Chronic Pain
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
170
Start Date
2027-04-01
Completion Date
2030-09-30
Last Updated
2026-07-24
Healthy Volunteers
No
Interventions
Mantram Repetition Program for PTSD + Pain
manualized Mantram Repetition Program adapted for Veterans with PTSD and chronic pain
Health Education while Living with Pain
manualized health and wellness psychoeducation and discussion group
Locations (1)
VA San Diego Healthcare System, San Diego, CA
San Diego, California, United States