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Effect of FPP on Cutaneous Barrier Integrity
Sponsor: University of Pittsburgh
Summary
This pilot study will test how Fermented Papaya Preparation (FPP) impacts overall TEWL of areas that commonly display diminished barrier function, such as the skin from face, arms, and hands. Areas of diminished barrier function are defined as those not visible to the eye but identified as areas of high transepidermal water loss (TEWL) as measured by a non-invasive pen-like device. A TEWL value of 20 or higher at a location would be considered high TEWL. Participants will attend 5 visits over 20 weeks, with 12-weeks of FPP treatment, and 8-weeks of follow-up.
Official title: Pilot Study of Fermented Papaya Preparation (FPP) Impact on Transepidermal Water Loss of Skin on Face, Arms, and Hands
Key Details
Gender
All
Age Range
50 Years - 75 Years
Study Type
INTERVENTIONAL
Enrollment
30
Start Date
2026-10
Completion Date
2028-07
Last Updated
2026-10-07
Healthy Volunteers
Yes
Interventions
Fermented Papaya Preparation (FPP)
Immun'Age Fermented Papaya Preparation
Locations (1)
McGowan Institute for Regenerative Medicine
Pittsburgh, Pennsylvania, United States