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Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract Infections
Sponsor: IRCCS Azienda Ospedaliero-Universitaria di Bologna
Summary
This study is designed to better understand how well a new antibiotic combination, cefepime/enmetazobactam (FEP/META), works in patients with complicated urinary tract infections that have spread to the bloodstream (bacteremia). These infections are caused by bacteria that are resistant to several commonly used antibiotics, including bacteria that produce extended-spectrum beta-lactamases (ESBLs) or OXA-48 carbapenemases. The main goal of the study is to compare cefepime/enmetazobactam with the best currently available antibiotic treatments to see how quickly blood cultures become negative after treatment begins, which is an important sign that the infection is improving.
Official title: Cefepime/Enmetazobactam for Bacteremic Complicated Urinary Tract Infections: an Observational Prospective Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
200
Start Date
2026-10-15
Completion Date
2029-10-15
Last Updated
2026-07-24
Healthy Volunteers
No
Locations (3)
IRCCS Azienda Ospedaliero-Universitaria di Bologna
Bologna, Italy, Italy
Azienda Ospedaliera di Rilievo Nazionale e di Alta Specializzazione (ARNAS) Garibaldi
Catania, Italy, Italy
ASST Fatebenefratelli Sacco
Milan, Italy, Italy