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RISE: Reducing Cancer and HIV Stigma Through Empowerment
Sponsor: M.D. Anderson Cancer Center
Summary
This multilevel randomized behavioral study evaluates participant- and provider-level stigma-reduction interventions in Zambia. Participant-level intervention: Women living with cervical cancer and HIV (WLC+H ) are randomized in a 2×2 factorial design of storytelling versus neutral videos and storytelling versus neutral disclosure interventions to assess effects on quality of life, anxiety, and depressive symptoms. Provider-level intervention: Healthcare workers are randomized to storytelling or neutral videos to assess changes in stigma and compassion. The study also evaluates participant -reported stigma and satisfaction with care before and after implementation of the provider intervention.
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
440
Start Date
2026-09-01
Completion Date
2030-08-31
Last Updated
2026-07-27
Healthy Volunteers
No
Conditions
Interventions
Neutral Video
Participants in the control group will watch neutral videos and describe objective, non-emotional objects/events
Storytelling
The storytelling intervention group will watch the storytelling videos and then describe objective, non-emotional objects/events.
Self disclosure
Participants will watch neutral videos and then talk/write about their cancer/HIV-related experiences to themselves.
Combination
The combination group will watch the storytelling videos and then talk/write about their cancer/HIV-related experiences to themselves.
Video
Participants (healthcare workers) will watch storytelling videos in a group setting, followed by a facilitated discussion and role-playing to enhance empathy and understanding.
Waitlist
Participants will watch unrelated presentations in a group setting while on a waitlist. They will receive the intervention after completing the post-test.
Locations (1)
UT MD Anderson
Houston, Texas, United States