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The Effect of Olive Leaf Extract Supplementation on Training-induced Skeletal Muscle Functional and Molecular Adaptations in Healthy Volunteers
Sponsor: University of Lausanne
Summary
The goal of this study is to investigate the effect of combining olive leaf extract supplementation with endurance training (moderate intensity continuous training or sprint interval training). We hypothesize that OLE supplementation during training, as compared to training alone with placebo, will translate into better performance outcomes. More specifically, we hypothesize that the additional benefits of OLE supplementation on performance will be mediated by improved mitochondrial characteristics in skeletal muscle and increased neural activation.
Key Details
Gender
All
Age Range
18 Years - 45 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2026-09-01
Completion Date
2029-12-31
Last Updated
2026-07-27
Healthy Volunteers
Yes
Conditions
Interventions
Olive leaf extract
A capsule containing 250 mg of an olive leaf extract preparation will be swallowed with a glass of water daily for 21 days.
Placebo
A capsule containing 336 mg of cellulose microcrystalline will be swallowed with a glass of water daily for 21 days.
Locations (1)
Bâtiment Synathlon, quartier UNIL-Centre
Lausanne, Switzerland