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RECRUITING
NCT07729969
NA

Early Cognitive Interventions in Digital Format for Cancer Survivors

Sponsor: Biogipuzkoa Health Research Institute

View on ClinicalTrials.gov

Summary

The aim of this study is to evaluate the usability and effectiveness of two professionally supervised home-based cognitive training interventions as part of an early rehabilitation protocol for cancer-related cognitive impairment. Participants will be randomized to one of the two intervention arms (computerized cognitive intervention or virtual reality cognitive intervention) or to the control group. Participants of the intervention groups will be assessed before and after the 10 weeks intervention or at equivalent time points for the control group. Comparisons between experimental and control participants, and between the participants in the two intervention arms, will be carried out to see which intervention is most effective and accepted.

Official title: Early Cognitive Interventions in Digital Format for Cancer Survivors - INCOTEM

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

110

Start Date

2026-06-08

Completion Date

2028-04-30

Last Updated

2026-07-28

Healthy Volunteers

No

Interventions

BEHAVIORAL

Computerized cognitive treatment

Online exercises that target the following functions: attention, processing speed, memory, spatial orientation, interpersonal skills and intelligence. Participants will follow an online cognitive training with the BrainHQ program for 10 weeks. Patients will complete exercises that target attention, executive function, memory and processing speed. They will be asked to train approximately 30 minutes per BrainHQ session, 5 times per week for 10 weeks, a total of 25 hours. Training progresses in an adaptive way, based on the progression of the participant.

BEHAVIORAL

Virtual reality cognitive training

A library of 15 cognitive exercises developed in virtual reality to train and monitor specific cognitive functions (memory, attention, task flexibility, information processing, orientation, and problem-solving) and motor control. Participants will follow a virtual reality cognitive training with the Enhance VR program for 10 weeks. Patients will complete exercises that target attention, executive function, memory and processing speed. Participants will be asked to train approximately 30 minutes per Enhance VR session, 4 times per week for 10 weeks, a total of 20 hours. Training progresses in an adaptive way, based on the progression of the participant.

Locations (3)

Hospital Universitario Basurto

Bilbao, Bizkaia, Spain

Hospital Universitario Galdakao-Usansolo

Galdakao, Bizkaia, Spain

Hospital Universitario Donostia

San Sebastián, Gipuzkoa, Spain