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Analysis of Renal Impairment Characteristics and High-Risk Factors in Chronic Hepatitis B Patients on Long-Term Oral Nucleos(t)Ide Analogues
Sponsor: Foshan Hospital of Traditional Chinese Medicine
Summary
This is a single-center retrospective observational study. A total of 300 patients with non-alcoholic fatty liver disease treated in our hospital will be included. We collect clinical data, laboratory indicators and imaging results, and analyze the correlation between long-term nucleoside antiviral drugs and renal function changes in patients. The study does not use any new intervention measures, and only conducts statistical analysis on existing medical record data.
Official title: Analysis of Renal Impairment Characteristics and High-Risk Factors in Patients With Chronic Hepatitis B Receiving Long-Term Oral Nucleos(t)Ide Analogues
Key Details
Gender
All
Age Range
18 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
300
Start Date
2024-09-04
Completion Date
2025-12-31
Last Updated
2026-07-28
Healthy Volunteers
No
Interventions
Long-term oral nucleos(t)ide analogs antiviral therapy
Oral nucleos(t)ide analog antiviral drugs, including tenofovir alafenamide, tenofovir disoproxil fumarate, entecavir, used for long-term treatment of chronic hepatitis B virus infection. This is a retrospective observational study analyzing renal safety after long-term antiviral treatment.
Locations (1)
Foshan Hospital of Traditional Chinese Medicine
Foshan, Guangdong, China