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Forced Oscillatory Technique for Bronchiolitis Obliterans Syndrome After Allogeneic Bone Marrow Transplantation
Sponsor: Hadassah Medical Organization
Summary
Bronchiolitis obliterans syndrome (BOS) is a severe pulmonary complication following allogeneic hematopoietic stem cell transplantation (HSCT). This prospective study evaluates the usefulness of the Forced Oscillation Technique (FOT) for the diagnosis, early detection, monitoring, and assessment of treatment response in patients undergoing allogeneic HSCT. FOT results will be compared with standard pulmonary function tests (spirometry, lung volumes, and DLCO).
Official title: Forced Oscillatory Technique for the Diagnosis, Monitoring, and Assessment of Treatment Response in Bronchiolitis Obliterans Syndrome Following Allogeneic Bone Marrow Transplantation
Key Details
Gender
All
Age Range
6 Months - Any
Study Type
INTERVENTIONAL
Enrollment
400
Start Date
2021-08-19
Completion Date
2030-12-30
Last Updated
2026-07-28
Healthy Volunteers
No
Conditions
Interventions
FOT - Forced Oscillation Technique
Forced Oscillation Technique (FOT) performed in addition to standard pulmonary function testing for the assessment of bronchiolitis obliterans syndrome after allogeneic hematopoietic stem cell transplantation
Locations (1)
Hadassah MO, Jerusalem, 9574869, Jerusalem,
Jerusalem, Israel