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RECRUITING
NCT07732010
PHASE4

TRYPTYR as a Treatment for Patients With Dry Eye Disease (DED)

Sponsor: NYU Langone Health

View on ClinicalTrials.gov

Summary

The purpose of this research study is to determine the effectiveness of TRYPTYR as a treatment for Dry Eye Disease. The primary efficacy variable is change from baseline in the Ocular Surface Disease Index (OSDI) at week 2. The co-primary efficacy variables are change from baseline in the National Eye Institute (NEI) scale of the cornea and NEI scale of the conjunctiva at 1 month (the third visit).

Official title: A Single Center Investigator Initiated Trial Using TRYPTYR as a Treatment for Patients With Dry Eye Disease

Key Details

Gender

All

Age Range

18 Years - Any

Study Type

INTERVENTIONAL

Enrollment

50

Start Date

2026-07-06

Completion Date

2027-05-25

Last Updated

2026-07-28

Healthy Volunteers

No

Interventions

DRUG

TRYPTYR (Acoltremon ophthalmic solution 0.003%)

TRYPTYR will be administered one drop in each eye twice daily (once every 12 hours) for 30 days.

Locations (1)

NYU Langone Health

New York, New York, United States