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Sedation Safety Assessment Using IPI Monitoring in Pediatric Hematologic Procedures
Sponsor: Ankara City Hospital Bilkent
Summary
Pediatric hematologic procedures such as lumbar puncture and bone marrow aspiration often require deep sedation due to pain and the need for immobility. Sedative and opioid combinations increase the risk of respiratory depression. Integrated Pulmonary Index (IPI) combines SpO₂, EtCO₂, respiratory rate, and heart rate into a single score and may allow earlier detection of respiratory compromise. This study aims to evaluate the safety and effectiveness of IPI monitoring in pediatric patients undergoing hematologic procedures under sedation with BIS monitoring.
Official title: Evaluation of Sedation Safety Using Integrated Pulmonary Index (IPI) Monitoring During Pediatric Hematologic Procedures Performed Under BIS Monitoring
Key Details
Gender
All
Age Range
2 Years - 18 Years
Study Type
OBSERVATIONAL
Enrollment
80
Start Date
2026-04-01
Completion Date
2026-06-09
Last Updated
2026-07-29
Healthy Volunteers
No
Interventions
Deep Sedation with IPI and BIS Monitoring
Standard sedation protocol including Midazolam (0.03 mg/kg), Fentanyl (1 mcg/kg), and Propofol (1-2 mg/kg). Monitoring includes standard ASA monitors plus Bispectral Index (BIS) and Integrated Pulmonary Index (IPI).
Locations (1)
Ankara Bilkent Şehir Hastanesi
Ankara, Çankaya, Turkey (Türkiye)