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Is Serum Irisin Level a Biomarker in Diabetic Polyneuropathy?
Sponsor: GÜLDEN ANATACA
Summary
Diabetic polyneuropathy is a common complication of type 2 diabetes mellitus associated with sensory impairment and functional disability. Irisin is a myokine that has been implicated in glucose metabolism and neuroprotection. This prospective observational case-control study aims to evaluate serum irisin concentrations in patients with diabetic polyneuropathy compared with diabetic patients without neuropathy and healthy controls, and to investigate whether serum irisin may serve as a biomarker for diabetic polyneuropathy.
Official title: Evaluation of Serum Irisin Levels as a Potential Biomarker in Patients With Diabetic Polyneuropathy: A Single-center Prospective Cross-sectional Observational Study
Key Details
Gender
All
Age Range
30 Years - 75 Years
Study Type
OBSERVATIONAL
Enrollment
81
Start Date
2026-07-30
Completion Date
2026-09-30
Last Updated
2026-07-29
Healthy Volunteers
Yes
Locations (1)
Kanuni Sultan Süleyman Training and Research Hospital
Istanbul, Turkey (Türkiye)