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NCT07734597

Is Serum Irisin Level a Biomarker in Diabetic Polyneuropathy?

Sponsor: GÜLDEN ANATACA

View on ClinicalTrials.gov

Summary

Diabetic polyneuropathy is a common complication of type 2 diabetes mellitus associated with sensory impairment and functional disability. Irisin is a myokine that has been implicated in glucose metabolism and neuroprotection. This prospective observational case-control study aims to evaluate serum irisin concentrations in patients with diabetic polyneuropathy compared with diabetic patients without neuropathy and healthy controls, and to investigate whether serum irisin may serve as a biomarker for diabetic polyneuropathy.

Official title: Evaluation of Serum Irisin Levels as a Potential Biomarker in Patients With Diabetic Polyneuropathy: A Single-center Prospective Cross-sectional Observational Study

Key Details

Gender

All

Age Range

30 Years - 75 Years

Study Type

OBSERVATIONAL

Enrollment

81

Start Date

2026-07-30

Completion Date

2026-09-30

Last Updated

2026-07-29

Healthy Volunteers

Yes

Locations (1)

Kanuni Sultan Süleyman Training and Research Hospital

Istanbul, Turkey (Türkiye)