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Effect of Trypan Blue on Corneal Endothelial Cell Count During Phacoemulsification
Sponsor: Hayat Abad Medical Complex, Peshawar
Summary
This randomized controlled trial evaluated the effect of trypan blue on corneal endothelial cell count in patients undergoing phacoemulsification for age-related cataract. Sixty participants were randomly assigned to undergo phacoemulsification either with trypan blue-assisted anterior capsule staining or without trypan blue. The primary objective was to compare postoperative corneal endothelial cell count between the two groups using specular microscopy to determine whether trypan blue has an effect on corneal endothelial cell loss during cataract surgery.
Key Details
Gender
All
Age Range
18 Years - 60 Years
Study Type
INTERVENTIONAL
Enrollment
60
Start Date
2024-03-22
Completion Date
2024-09-22
Last Updated
2026-07-30
Healthy Volunteers
No
Conditions
Interventions
Trypan Blue
Trypan blue was administered intracamerally to stain the anterior lens capsule before continuous curvilinear capsulorhexis during phacoemulsification. The dye was removed after adequate staining, and the remaining surgical procedure was completed using the standard technique.
Phacoemulcification
Standard phacoemulsification with posterior chamber intraocular lens implantation performed using a standardized surgical technique
Locations (1)
Department of Ophthalmology, Hayatabad Medical Complex, Peshawar, Pakistan
Peshawar, KPK, Pakistan