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Tissue Adhesive vs Silk Sutures After Mandibular Third Molar Extraction
Sponsor: University of Turin, Italy
Summary
Summary: This study compares two methods used to close the gum after the surgical removal of impacted lower wisdom teeth: a medical tissue adhesive and traditional silk sutures. Both closure techniques are evaluated for postoperative pain, bleeding, healing, and the local inflammatory response.
Official title: Clinical and Immunological Evaluation of Tissue Adhesive vs. Silk Suture for Primary Closure of Surgical Flaps After Mandibular Third Molar Extractions: a Split-mouth Randomized Controlled Trial
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
INTERVENTIONAL
Enrollment
47
Start Date
2026-01-10
Completion Date
2026-07-10
Last Updated
2026-07-30
Healthy Volunteers
No
Conditions
Interventions
mandibular third molar extraction - surgical glue
The experimental intervention consists of primary flap closure using n-hexyl-cyanoacrylate tissue adhesive (Ifabond® Glue) following surgical extraction of impacted mandibular third molars. The adhesive is applied directly along the wound margins under dry conditions, without the use of sutures, allowing polymerization to achieve wound approximation.
mandibular third molar extraction - silk suture
The control intervention consists of primary flap closure using three interrupted 3/0 silk sutures following surgical extraction of impacted mandibular third molars. After repositioning the mucoperiosteal flap, interrupted sutures are placed to achieve primary wound closure according to standard surgical practice.
Locations (1)
CIR Dental School
Torino, Italy