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Validation of an Effort-Based Cough Peak Flow Algorithm to Predict Extubation Outcomes
Sponsor: Hospital H+ Queretaro
Summary
This study aims to prospectively validate the diagnostic accuracy of an effort-stratified Cough Peak Flow (CPF) decision algorithm for predicting extubation failure, maintaining strict blinding of the clinical team. The model classifies patients by neurological status and uses an effort-based approach, including a "Gray Zone" (40-59 L/min) managed by tidal volume evaluation.
Official title: Validation of an Effort-Based Cough Peak Flow Algorithm to Predict Extubation Outcomes in the ICU: A Prospective Blinded Cohort Study
Key Details
Gender
All
Age Range
18 Years - Any
Study Type
OBSERVATIONAL
Enrollment
150
Start Date
2026-07-01
Completion Date
2026-11-30
Last Updated
2026-07-30
Healthy Volunteers
Not specified
Conditions
Interventions
Observational measurement of Cough Peak Flow and Tidal Volume
Patients undergo standardized CPF and pre-cough tidal volume (VT) measurements prior to extubation. Measurements are stratified by cooperation level (Voluntary vs. Reflex).