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NOT YET RECRUITING
NCT07737613
EARLY_PHASE1

Acute Effects of Estradiol Administration on Brain Function During Fear Learning

Sponsor: University of Arizona

View on ClinicalTrials.gov

Summary

The goal of current study is to better understand how fear is processed in the brain and how these processes are influenced by cognition and hormones. This research will focus specifically on postmenopausal female adults, because age-related changes in cognition and declining estrogen levels may contribute to anxiety symptoms and PTSD risk later in life.

Official title: Neuroimaging Study of Fear Learning: Effects of Estrogen

Key Details

Gender

FEMALE

Age Range

60 Years - Any

Study Type

INTERVENTIONAL

Enrollment

30

Start Date

2026-08

Completion Date

2027-12

Last Updated

2026-07-30

Healthy Volunteers

Yes

Interventions

DRUG

estradiol

oral 2mg tablet of estradiol