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NCT07737639

Evaluating Facial Skin Quality Changes Post-Lipofilling

Sponsor: L'Oreal

View on ClinicalTrials.gov

Summary

The goal of this prospective observational study is to evaluate changes in facial skin quality and identify predictive biological markers in donor adipose tissue in healthy women undergoing autologous facial fat transfer. The main questions it aims to answer are: How does full-face lipofilling alter clinical signs of aging, such as wrinkles, sagging, and skin texture, over a 6-month period? Which baseline biological characteristics (e.g., cellular stemness, extracellular matrix remodeling, angiogenesis) within the donor fat graft predict these clinical skin quality outcomes? Participants will: Undergo a standard full-face autologous fat transfer (lipofilling) procedure. Attend follow-up evaluation visits at 1.5, 3, and 6 months post-procedure. Undergo non-invasive clinical and instrumental skin assessments (e.g., standardized photography, 3D topography, echography, and cutometry). Complete self-assessment questionnaires regarding perceived skin changes and overall satisfaction with the procedure.

Official title: A MONOCENTER, OPEN STUDY TO ASSESS THE CHANGES INDUCED BY A LIPOFILLING PROCEDURE ON FACIAL SKIN QUALITY AND AGEING SIGNS IN WOMEN

Key Details

Gender

FEMALE

Age Range

30 Years - Any

Study Type

OBSERVATIONAL

Enrollment

15

Start Date

2021-01-10

Completion Date

2024-09-10

Last Updated

2026-07-30

Healthy Volunteers

Yes

Conditions

Locations (1)

L'Oréal

Aulnay-sous-Bois, France