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Lactic Acid Bacteria for Reducing Blue Light-Induced Eye Fatigue
Sponsor: Synbio Tech Inc.
Summary
With the widespread use of digital devices and prolonged screen exposure, digital eye strain (DES), also known as computer vision syndrome, has become a global public health concern. Emerging evidence suggests that the gut-eye axis may play an important role in ocular health, as gut microbiota imbalance is associated with systemic inflammation and oxidative stress. Specific probiotics may help alleviate eye discomfort through modulation of immune responses and enhancement of antioxidant defense mechanisms. This randomized, double-blind, placebo-controlled study aims to evaluate the efficacy of supplementation with specific probiotics, Bifidobacterium longum BL531 and Lactobacillus reuteri LR1349, in improving digital eye strain symptoms in adults.
Official title: The Application of Lactic Acid Bacteria on Reducing Blue Light-Induced Eye Fatigue in Middle-Aged Adults
Key Details
Gender
All
Age Range
20 Years - 65 Years
Study Type
INTERVENTIONAL
Enrollment
150
Start Date
2026-09-01
Completion Date
2027-12-31
Last Updated
2026-07-30
Healthy Volunteers
Yes
Conditions
Interventions
Placebo
Maltodextrin
BL531_low dose
1×10\^10 cfu/day
BL531_high dose
2.5×10\^10 cfu/day
LR1349_low dose
1×10\^10 cfu/day
LR1349_high dose
2.5×10\^10 cfu/day
Locations (1)
National Taiwan Normal University
Taipei, Taiwan